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Institute of Experimental Immunology Inflammation Research

10 Recent original Publications:

  1. Ingelfinger, Florian et al. “Twin study dissects CXCR3+ memory B cells as non-heritable feature in multiple sclerosis.” Med (New York, N.Y.) vol. 5,4 (2024): 368-373.e3. doi:10.1016/j.medj.2024.02.013
  2. Wertheimer, Tobias et al. “IL-23 stabilizes an effector Treg cell program in the tumor microenvironment.” Nature immunology vol. 25,3 (2024): 512-524. doi:10.1038/s41590-024-01755-7
  3. Ulutekin, Can et al. “B cell depletion attenuates CD27 signaling of T helper cells in multiple sclerosis.” Cell reports. Medicine vol. 5,1 (2024): 101351. doi:10.1016/j.xcrm.2023.101351
  4. Andreadou, Myrto et al. “IL-12 sensing in neurons induces neuroprotective CNS tissue adaptation and attenuates neuroinflammation in mice.” Nature Neuroscience , vol. 26,10 (2023): 1701-1712, doi:10.1038/s41593-023-01435-z
  5. Nuñez, Nicolás Gonzalo et al. “High-dimensional analysis of 16 SARS-CoV-2 vaccine combinations reveals lymphocyte signatures correlating with immunogenicity.” Nature Immunology , vol. 24,6 (2023): 941-954, doi:10.1038/s41590-023-01499-w
  6. Kreutmair, Stefanie et al. “Preexisting comorbidities shape the immune response associated with severe COVID-19.” The Journal of allergy and clinical immunology, vol. 150,2 (2022): 312-324, https://doi.org/10.1016/j.jaci.2022.05.019
  7. Ingelfinger, Florian et al. “Twin study reveals non-heritable immune perturbations in multiple sclerosis.” Nature, 10.1038/s41586-022-04419-4. 16 Feb. 2022.
  8. Amorim, Ana et al. “IFNγ and GM-CSF control complementary differentiation programs in the monocyte-to-phagocyte transition during neuroinflammation.” Nature immunology vol. 23,2 (2022): 217-228.
  9. Krishnarajah, Sinduya et al. Single-cell profiling of immune system alterations in lymphoid, barrier and solid tissues in aged mice Nature Aging (2021).
  10. Zwicky, Pascale et al. “IL-12 regulates type 3 immunity through interfollicular keratinocytes in psoriasiform inflammation.” Science immunology vol. 6,64 (2021): eabg9012.
  11. Kreutmair, Stefanie et al. “Distinct immunological signatures discriminate severe COVID-19 from non-SARS-CoV-2-driven critical pneumonia.” Immunity vol. 54,7 (2021): 1578-1593.e5

Selected Reviews:

  1. Gogoleva, Violetta S et al. “Mononuclear phagocytes in autoimmune neuroinflammation.” Trends in immunology vol. 45,10 (2024): 814-823. doi:10.1016/j.it.2024.08.005
  2. Becher, Burkhard et al. “Targeting cytokine networks in neuroinflammatory diseases.” Nature reviews. Drug discovery vol. 23,11 (2024): 862-879. doi:10.1038/s41573-024-01026-y
  3. Kienzler, Jenny C, and Burkhard Becher. “Immunity in malignant brain tumors: Tumor entities, role of immunotherapy, and specific contribution of myeloid cells to the brain tumor microenvironment.” European journal of immunology vol. 54,2 (2024): e2250257. doi:10.1002/eji.202250257
  4. Mundt S, Greter M, Becher B. The CNS mononuclear phagocyte system in health and disease. Neuron. 2022;110(21):3497-3512.
  5. Tuzlak, Selma et al. Repositioning TH cell polarization from single cytokines to complex help. Nature immunology vol. 22,10 (2021): 1210-1217.

Weiterführende Informationen

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Publications

You will find an up-to-date list of our publications on the PubMed website.